Classification issues in malformations caused by abnormalities of cortical development

Neurosurg Clin N Am. 2002 Jan;13(1):1-16, vii. doi: 10.1016/s1042-3680(02)80002-x.

Abstract

Malformations caused by abnormalities of cortical development (MCDs) as a group are now widely recognized as a key cause of medically refractory epilepsies, often leading to a consideration of surgical treatment. A practical classification scheme including histopathologic, imaging, and, if possible, clinical-electrographic features of the various different types of MCDs, will be important to the delineation of surgical strategies and anticipation of medical and surgical prognoses. A proposal of such a scheme with emphasis on the focal cortical dysplasias is given in the hopes that it will reopen the debate on the best way to classify these disorders.

MeSH terms

  • Cerebral Cortex / abnormalities*
  • Cerebral Cortex / pathology
  • Cerebral Cortex / surgery
  • Epilepsy / classification
  • Epilepsy / congenital
  • Epilepsy / pathology
  • Humans
  • Neurons / pathology