Outbreak of scarlet fever caused by an erythromycin-resistant Streptococcus pyogenes emm22 genotype strain in a day-care center

Pediatr Infect Dis J. 2001 Aug;20(8):807-9. doi: 10.1097/00006454-200108000-00019.

Abstract

We report an outbreak of scarlet fever and pharyngeal colonization with Streptococcus pyogenes in a day-care center in Mexico City. The outbreak strain was resistant to erythromycin but susceptible to clindamycin. T-type 11,12 serotype was found in eight isolates, from two patients and six carriers, which had the emm22 gene. The recognition of streptococci resistant to macrolides causing outbreaks has implications for infection control and for improving antibiotic prescribing patterns in the day-care setting.

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics*
  • Child Day Care Centers*
  • Child, Preschool
  • Disease Outbreaks*
  • Drug Resistance, Bacterial
  • Erythromycin / pharmacology*
  • Genotype
  • Humans
  • Infant
  • Membrane Proteins / genetics*
  • Mexico / epidemiology
  • Scarlet Fever / epidemiology*
  • Scarlet Fever / microbiology
  • Streptococcus pyogenes / classification
  • Streptococcus pyogenes / drug effects*
  • Streptococcus pyogenes / genetics

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Emm22 protein,Streptococcus pyogenes
  • Membrane Proteins
  • Erythromycin