Synthesis of Substituted Piperidines from N,N-Bis[(benzotriazol-1-yl)methyl]amines

Alan R. Katritzky; Zhushou Luo; Xi-Lin Cui

doi:10.1021/jo982356n

Synthesis of Substituted Piperidines from N,N-Bis[(benzotriazol-1-yl)methyl]amines

J Org Chem. 1999 Apr 30;64(9):3328-3331. doi: 10.1021/jo982356n.

Authors

Alan R. Katritzky¹, Zhushou Luo, Xi-Lin Cui

Affiliation

¹ Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200.

PMID: 11674438
DOI: 10.1021/jo982356n

Abstract

N,N-Bis[(benzotriazol-1-yl)methyl]benzylamines and N,N-bis[(benzotriazol-1-yl)methyl](p-N',N'-dimethylphenyl)amine on reaction with allyltrimethylsilanes yielded substituted piperidines. Other N,N-bis[(benzotriazol-1-yl)methyl]anilines (unsubstituted and p-CH(3), OCH(3), Cl) gave julolidines (2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij] quinoline).