Computational aberration correction for an arbitrary linear imaging system

Phys Rev Lett. 2001 Sep 17;87(12):123902. doi: 10.1103/PhysRevLett.87.123902. Epub 2001 Aug 30.

Abstract

We show that aberration corrections can be made in any arbitrary linear imaging system provided the aberrations are well characterized and at least one of these aberrations can be independently varied in a well-controlled manner. We derive a generalization of the Schrödinger equation for wave propagation in aberration space assuming forward scattering. Transport equations in aberration space are derived. A general iterative algorithm which can retrieve the phase, and is robust in the presence of noise, is also derived. This is demonstrated using simulated data pertinent to electron microscopy, from a series of images with differing spherical aberration.