Copper-catalyzed coupling reaction of terminal alkynes with aryl- and alkenyliodonium salts

S K Kang; S K Yoon; Y M Kim

doi:10.1021/ol0162825

Copper-catalyzed coupling reaction of terminal alkynes with aryl- and alkenyliodonium salts

Org Lett. 2001 Aug 23;3(17):2697-9. doi: 10.1021/ol0162825.

Authors

S K Kang¹, S K Yoon, Y M Kim

Affiliation

¹ Department of Chemistry and BK-21 School of Molecular Science, Sungkyunkwan University, Suwon 440-746, Korea. skkang@chem.skku.ac.kr

PMID: 11506612
DOI: 10.1021/ol0162825

Abstract

[reaction: see text]. The copper iodide-catalyzed cross-coupling of terminal alkynes with hypervalent iodonium salts was accomplished with CuI (10 mol %) and NaHCO3 (2 equiv) in DME/H2O (4:1) at room temperature for 30 min to afford arylalkynes or enynes under mild conditions.