In vitro assessment of the antimicrobial action and the mechanical ability of chlorhexidine gel as an endodontic irrigant

J Endod. 2001 Jul;27(7):452-5. doi: 10.1097/00004770-200107000-00004.

Abstract

The objective of this study was to assess the chlorhexidine gluconate gel as an endodontic irrigant. First the ability of chlorhexidine gel to disinfect root canals contaminated in vitro with Enterococcus faecalis was investigated. A scanning electron microscope was also used to evaluate its cleansing ability compared with endodontic irrigants commonly used, such as sodium hypochlorite and chlorhexidine gluconate liquid. The results indicated that the chlorhexidine gel produced a cleaner root canal surface and had an antimicrobial ability comparable with that obtained with the other solutions tested. It was concluded that chlorhexidine gluconate in gel form has potential for use as an endodontic irrigant.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents, Local / therapeutic use*
  • Chi-Square Distribution
  • Chlorhexidine / analogs & derivatives
  • Chlorhexidine / therapeutic use*
  • Dental Pulp Cavity / drug effects*
  • Dental Pulp Cavity / microbiology
  • Dental Pulp Cavity / ultrastructure
  • Detergents / therapeutic use
  • Disinfectants / therapeutic use
  • Enterococcus faecalis / drug effects
  • Gels
  • Humans
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Root Canal Irrigants / therapeutic use*
  • Sodium Hypochlorite / therapeutic use
  • Solutions
  • Statistics as Topic

Substances

  • Anti-Infective Agents, Local
  • Detergents
  • Disinfectants
  • Gels
  • Root Canal Irrigants
  • Solutions
  • Sodium Hypochlorite
  • chlorhexidine gluconate
  • Chlorhexidine