Significance of the solid component in predicting malignancy in ovarian cystic teratomas: diagnostic considerations

J Ultrasound Med. 2001 Aug;20(8):859-66; quiz 867. doi: 10.7863/jum.2001.20.8.859.

Abstract

Objective: To determine whether gray scale characteristics of the solid components of cystic ovarian teratomas exist that could differentiate more common benign forms from malignant variants.

Methods: We retrospectively reviewed the sonographic images of 188 ovarian teratomas that contain at least a 25% cystic component and correlated the images with the final diagnosis. Features of the solid component assessed included its echo texture, overall appearance, shape, size, and internal homogeneity.

Results: One-hundred seventy-seven teratomas were benign, and 11 were malignant; among the malignant masses, 7 were high grade. Of the benign forms, 155 solid components (88%) were hyperechoic, 168 (95%) were focal in appearance, 105 (59%) were nodular in shape, and 123 (69%) were uniformly solid. Of the malignant types, 9 solid components (82%) were isoechoic, 6 (55%) had branching, 6 (55%) were irregular in shape, and 8 (73%) were uniformly solid. Five malignant teratomas (45% overall and 71% of high-grade subtypes) had branching isoechoic components. Only 2 benign teratomas (1%) had isoechoic components that branched.

Conclusions: The presence of a branching isoechoic component in a cystic ovarian teratoma may suggest malignancy.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cell Transformation, Neoplastic
  • Female
  • Humans
  • Middle Aged
  • Neoplasm Invasiveness
  • Ovarian Cysts / diagnostic imaging*
  • Ovarian Neoplasms / diagnostic imaging*
  • Ovarian Neoplasms / pathology
  • Retrospective Studies
  • Teratoma / diagnostic imaging*
  • Teratoma / pathology
  • Ultrasonography