Abstract
A 45-year-old man presented with progressively worsening vitreitis of 1 week's duration. Treatment for cat-scratch disease 3 years prior to presentation and persistent vitreitis led to vitrectomy, and analysis of the vitrectomy specimen revealed inflammatory cells and necrotic debris; polymerase-chain-reaction analysis of the vitreous fluid sample, done by use of a novel heminested protocol, demonstrated the presence of Bartonella henselae DNA. Treatment with doxycycline led to improvement in the intraocular inflammation but resulted in a poor visual outcome.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Acute Disease
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Adult
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Anti-Bacterial Agents / therapeutic use
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Bartonella henselae / genetics
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Bartonella henselae / isolation & purification*
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Cat-Scratch Disease / diagnosis*
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Cat-Scratch Disease / drug therapy
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DNA, Bacterial / isolation & purification
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Diagnosis, Differential
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Doxycycline / therapeutic use
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Endophthalmitis / drug therapy
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Endophthalmitis / microbiology*
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Humans
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Male
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Polymerase Chain Reaction
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Treatment Outcome
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Visual Acuity
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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Doxycycline