Distribution of quorum-sensing genes in the Burkholderia cepacia complex

Infect Immun. 2001 Jul;69(7):4661-6. doi: 10.1128/IAI.69.7.4661-4666.2001.

Abstract

The distribution of quorum-sensing genes among strains from seven genomovars of the Burkholderia cepacia complex was examined by PCR. cepR and cepI were amplified from B. cepacia genomovars I and III, B. stabilis, and B. vietnamiensis. cepR was also amplified from B. multivorans and B. cepacia genomovar VI. bviIR were amplified from B. vietnamiensis. All genomovars produced N-octanoyl-L-homoserine lactone and N-hexanoyl-L-homoserine lactone. B. vietnamiensis and B. cepacia genomovar VII produced additional N-acyl-L-homoserine lactones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Butyrolactone / analogs & derivatives*
  • 4-Butyrolactone / biosynthesis
  • Amino Acid Sequence
  • Bacterial Proteins / genetics*
  • Base Sequence
  • Burkholderia / genetics
  • Burkholderia cepacia / genetics*
  • Genes, Bacterial*
  • Homoserine / analogs & derivatives
  • Homoserine / biosynthesis
  • Lactones
  • Ligases*
  • Molecular Sequence Data
  • Sequence Homology, Amino Acid

Substances

  • Bacterial Proteins
  • CepR protein, Burkholderia
  • Lactones
  • N-hexanoyl-L-homoserine lactone
  • N-octanoylhomoserine lactone
  • homoserine lactone
  • Homoserine
  • Ligases
  • N-acylhomoserine lactone synthase
  • 4-Butyrolactone

Associated data

  • GENBANK/AF296284
  • GENBANK/AF333002
  • GENBANK/AF333003
  • GENBANK/AF333004
  • GENBANK/AF333005
  • GENBANK/AF333006
  • GENBANK/AF333007
  • GENBANK/AF333008
  • GENBANK/AF337814