[Post-traumatic bacterial meningitis]

Przegl Lek. 2000;57(12):699-701.
[Article in Polish]

Abstract

10 patients with posttraumatic bacterial meningitis were treated in the Department of Infectious Diseases of the Jagielloniam University--Collegium Medicum during the period of 63 months. Traffic accidents were responsible for 80% of all cases of trauma. The most common place of injury was the base of anterior cranial fossa. Infecting agent was established in 8 cases. Gram-positive aerobic cocci (Streptococcus pneumoniae, Enterococcus faecalis, and Enterococcus spp.) were found in 4 patients, Gram-negative aerobic cocci (Neisseria meningitidis) in 2 patients, and Gram-negative aerobic rods (Acinetobacter baumanii, Pseudomonas aeruginosa, Klebsiella spp, Escherichia coli) in 3 patients. Streptococcus pneumoniae was still highly sensitive to penicillin, ampicillin and cefotaxime. Enterococcus faecalis and Enterococcus spp. were sensitive to vancomycin and teicoplanin. Neisseria meningitidis was sensitive to penicillin, cefotaxime, amoxicillin/clavulonate. Gram negative aerobic rods were sensitive to third-generation cephalosporins, carbapenems and aminoglycosides. Among 10 patients treated for posttraumatic bacterial meningitis 1 patient died and in 1 preserved vegetative state was diagnosed. In 4 patients severe or moderate disabilities developed, however 4 recovered completely. 6 patients after regression of the CNS infection were qualified to neurosurgical intervention. In 3 patients reconstructive operation of the basis of anterior cranial fossa with tissue glue Beriplast P. was done, the recovery was complete. 3 patients didn't agree to surgical operation, and we don't know what has happened with them. They have not come to the control visit.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Cranial Fossa, Posterior / injuries
  • Cranial Fossa, Posterior / surgery
  • Drug Resistance, Microbial
  • Follow-Up Studies
  • Gram-Negative Aerobic Bacteria / drug effects
  • Gram-Negative Aerobic Bacteria / isolation & purification
  • Head Injuries, Closed / complications*
  • Humans
  • Meningitis, Bacterial / microbiology*
  • Meningitis, Bacterial / therapy*
  • Middle Aged
  • Treatment Outcome