Diabetes control by subcutaneous insulin infusion (CSII) by an insulin pump becomes the therapeutic option, which most closely mimics the physiologic insulin secretion pattern. It may bring glycemia close to normal levels even in cases where the standard injection insulin therapy fails. After CSII installation the mean daily dose of insulin can be reduced and the compensation of diabetes improves (decreases). CSII is usually installed in diabetic patients where the disease cannot be sufficiently controlled, namely in patients with "dawn phenomenon", severe hypoglycemia, and progression of diabetic complications. Results of long-term follow-up study of CSII-treated diabetic patients at our department (IKEM) confirmed the high efficacy of this method and the minimal incidence of therapy-related complications (severe hypoglycemia, ketoacidosis, body weight increase, technical complications).