Genetic and environmental influences on anorexia nervosa syndromes in a population-based twin sample

Psychol Med. 2001 May;31(4):737-40. doi: 10.1017/s0033291701003725.

Abstract

Background: Genetic and environmental influences on broadly-defined anorexia nervosa (AN) syndrome were examined in a population-based twin sample.

Methods: AN syndrome was assessed in 672 female 17 year-old twins using structured interviews and a self-report questionnaire.

Results: Twenty-six probands with AN syndrome were identified. Biometrical model-fitting analyses indicated that genetic and non-shared environmental factors accounted for 74% and 26% of the variance in AN syndrome, respectively.

Conclusions: Findings support previous research indicating significant genetic and non-shared environmental influences on AN syndromes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Twin Study

MeSH terms

  • Adolescent
  • Anorexia Nervosa / etiology
  • Anorexia Nervosa / genetics*
  • Environment
  • Female
  • Humans
  • Regression Analysis
  • Risk Factors