Metabolism of tyrosine and tryptophan--new genes for old pathways

Curr Opin Plant Biol. 2001 Jun;4(3):234-40. doi: 10.1016/s1369-5266(00)00166-7.

Abstract

Tyrosine and tryptophan are precursors for the plant defense compounds dhurrin and indole glucosinolates, respectively. In addition, tryptophan is a precursor for the essential phytohormone indole-3-acetic acid. Recent advances in understanding the biosynthesis of these compounds have come from the characterization of enzymes that catalyze the N-hydroxylation of the precursor amino acid to the oxime intermediate. Furthermore, enzymes catalyzing subsequent biosynthetic steps have also been identified.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Cytochrome P-450 Enzyme System / genetics
  • Cytochrome P-450 Enzyme System / metabolism
  • Glucosides / metabolism
  • Glucosinolates / metabolism
  • Hydroxylation
  • Indoleacetic Acids / metabolism*
  • Mixed Function Oxygenases / genetics
  • Mixed Function Oxygenases / metabolism
  • Nitriles / metabolism
  • Oximes / metabolism*
  • Plant Growth Regulators / metabolism
  • Plant Proteins / metabolism
  • Tryptophan / metabolism*
  • Tyrosine / metabolism*

Substances

  • Glucosides
  • Glucosinolates
  • Indoleacetic Acids
  • Nitriles
  • Oximes
  • Plant Growth Regulators
  • Plant Proteins
  • indole-3-aldehyde oxime
  • Tyrosine
  • indoleacetic acid
  • Tryptophan
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • cytochrome P450TYR
  • dhurrin