Abstract
Tyrosine and tryptophan are precursors for the plant defense compounds dhurrin and indole glucosinolates, respectively. In addition, tryptophan is a precursor for the essential phytohormone indole-3-acetic acid. Recent advances in understanding the biosynthesis of these compounds have come from the characterization of enzymes that catalyze the N-hydroxylation of the precursor amino acid to the oxime intermediate. Furthermore, enzymes catalyzing subsequent biosynthetic steps have also been identified.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Cytochrome P-450 Enzyme System / genetics
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Cytochrome P-450 Enzyme System / metabolism
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Glucosides / metabolism
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Glucosinolates / metabolism
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Hydroxylation
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Indoleacetic Acids / metabolism*
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Mixed Function Oxygenases / genetics
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Mixed Function Oxygenases / metabolism
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Nitriles / metabolism
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Oximes / metabolism*
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Plant Growth Regulators / metabolism
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Plant Proteins / metabolism
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Tryptophan / metabolism*
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Tyrosine / metabolism*
Substances
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Glucosides
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Glucosinolates
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Indoleacetic Acids
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Nitriles
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Oximes
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Plant Growth Regulators
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Plant Proteins
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indole-3-aldehyde oxime
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Tyrosine
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indoleacetic acid
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Tryptophan
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Cytochrome P-450 Enzyme System
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Mixed Function Oxygenases
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cytochrome P450TYR
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dhurrin