Atopic signs and symptoms: assessing the 'atopy score' concept

Dermatology. 2001;202(1):4-8. doi: 10.1159/000051576.

Abstract

Background: Score concepts have been suggested for the standardised diagnosis of atopic dermatitis, incorporating various anamnestic and clinical minor criteria of atopy, including the 'Erlangen Score', developed in the hospital-based setting of a dermatitis clinic.

Objective: To evaluate the properties of this score in the context of a population-based epidemiological study.

Methods: The association between relevant atopic criteria and previous or current flexural eczema was evaluated in 2,352 hairdressing apprentices.

Results: The association was not as strong as in the patient-based studies, comparing the respective odds ratios. Accordingly, the discriminating power of the Erlangen Score was poor, resulting in low sensitivity (55.7%) and specificity (73.8%) for, e.g., 8 points as cutpoint.

Conclusion: While the score appears useful to summarise minor criteria, the individual relevance of its point values should not be overestimated in view of a low positive predictive value in a population (compared to a clinical) setting.

MeSH terms

  • Adolescent
  • Adult
  • Cohort Studies
  • Dermatitis, Atopic / epidemiology*
  • Dermatitis, Atopic / etiology
  • Dermatitis, Atopic / pathology
  • Dermatitis, Occupational / epidemiology*
  • Dermatitis, Occupational / etiology
  • Dermatitis, Occupational / pathology
  • Female
  • Germany / epidemiology
  • Hair Preparations / adverse effects
  • Humans
  • Male
  • Prevalence
  • Prospective Studies
  • Severity of Illness Index
  • Statistics as Topic
  • Surveys and Questionnaires

Substances

  • Hair Preparations