Abstract
We studied the respiratory effects of the administration of either 5% halothane or 8% sevoflurane in 70% nitrous oxide (N2O) for 5 min in 21 boys aged 1-5 years. A similar degree of ventilatory depression was noted with both agents. Minute volume fell by approximately 50% as a result of a reduction in tidal volume despite an increase in respiratory rate.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
MeSH terms
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Anesthesia, Epidural
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Anesthesia, Inhalation / adverse effects*
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Anesthetics, Inhalation / adverse effects*
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Child, Preschool
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Depression, Chemical
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Halothane / pharmacology*
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Humans
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Infant
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Male
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Methyl Ethers / pharmacology*
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Respiration / drug effects*
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Sevoflurane
Substances
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Anesthetics, Inhalation
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Methyl Ethers
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Sevoflurane
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Halothane