Bi-stable transcriptional circuitry and GATA-3 auto-activation in Th2 commitment

Cold Spring Harb Symp Quant Biol. 1999:64:585-8. doi: 10.1101/sqb.1999.64.585.

Authors

K M Murphy¹, W Ouyang, S Ranganath, T L Murphy

Affiliation

¹ Pathology Department, Washington University School of Medicine, Howard Hughes Medical Institute, St. Louis, Missouri 63110, USA.

PMID: 11232335
DOI: 10.1101/sqb.1999.64.585

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Animals
Cell Differentiation
DNA-Binding Proteins / genetics*
GATA3 Transcription Factor
Humans
Interleukin-4 / metabolism
Mice
Signal Transduction
Th2 Cells / cytology*
Th2 Cells / immunology
Th2 Cells / metabolism*
Trans-Activators / genetics*
Transcriptional Activation

Substances

DNA-Binding Proteins
GATA3 Transcription Factor
GATA3 protein, human
Gata3 protein, mouse
Trans-Activators
Interleukin-4