Improved bone regeneration and root coverage using a resorbable membrane with physically assisted cell migration and DFDBA

Int J Periodontics Restorative Dent. 2000 Aug;20(4):398-411.

Abstract

Twelve patients with 2 Miller Class I or II buccal recession defects measuring > or = 3.0 mm were treated using the principles of guided tissue regeneration and followed for 12 months. The effectiveness of a polylactide (Guidor) resorbable membrane (GA sites) was compared to a combination treatment of polylactide membrane plus polyglactin root-lining mesh (Vicryl) and demineralized freeze-dried bone allograft (DFDBA) (GVB sites) designed to enhance cell migration and bone regeneration. There was 90% mean soft tissue root coverage for the GVB sites and 78% for the GA sites. The mean osseous dehiscence area coverage with hard tissue was 75% for GVB sites and 30% for GA sites.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Absorbable Implants*
  • Adult
  • Alveolar Bone Loss / surgery
  • Bone Regeneration*
  • Bone Transplantation* / methods
  • Cell Movement
  • Decalcification Technique
  • Dental Plaque Index
  • Female
  • Follow-Up Studies
  • Freeze Drying
  • Gingival Recession / surgery*
  • Guided Tissue Regeneration, Periodontal*
  • Humans
  • Male
  • Membranes, Artificial*
  • Middle Aged
  • Observer Variation
  • Periodontal Index
  • Polyesters
  • Polyglactin 910
  • Reproducibility of Results
  • Single-Blind Method
  • Statistics as Topic
  • Tissue Preservation
  • Tooth Root / surgery*
  • Transplantation, Homologous

Substances

  • Membranes, Artificial
  • Polyesters
  • Polyglactin 910
  • poly(lactide)