Preclinical and phase I clinical studies with Ckd-602, a novel camptothecin derivative

Ann N Y Acad Sci. 2000:922:324-5. doi: 10.1111/j.1749-6632.2000.tb07055.x.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / pharmacokinetics
  • Antineoplastic Agents / pharmacology*
  • Camptothecin / adverse effects*
  • Camptothecin / analogs & derivatives*
  • Camptothecin / pharmacokinetics
  • Camptothecin / pharmacology*
  • Dose-Response Relationship, Drug
  • Drug Screening Assays, Antitumor
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / metabolism
  • Topoisomerase I Inhibitors
  • Tumor Cells, Cultured / drug effects

Substances

  • Antineoplastic Agents
  • Topoisomerase I Inhibitors
  • belotecan
  • Camptothecin