Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder

Am J Med Genet. 2000 Dec 4;96(6):781-3.

Abstract

Large pedigrees can pose a problem for GENEHUNTER linkage analysis software. Differences in two-point and multipoint lodscores were observed when comparing GENEHUNTER to other linkage software. Careful consideration must be given when selecting linkage analysis programs. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:781-783, 2000.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chromosome Mapping
  • Genetic Linkage*
  • Genetic Markers
  • Humans
  • Lod Score
  • Panic Disorder / genetics*
  • Pedigree
  • Software*

Substances

  • Genetic Markers