The pathologist's view point. Part II --aggressive lymphomas

Haematologica. 2000 Dec;85(12):1308-21.

Abstract

Background and objectives: The REAL/WHO classification constitutes a new tool for the better understanding and treatment of malignant lymphomas. The authors focus on the key features of aggressive B- and T-cell lymphomas, aiming to contribute to the cross-talk between pathologists and clinicians.

Data sources and methods: Each lymphoma entity is analyzed on the basis of the most representative contributions in the literature and the authors' experience gained in studying more than 20,000 lymphoid tumors over a 20-year period.

Results: Guidelines for diagnosis and areas of interest for future clinico-pathologic studies are identified and discussed. Within this context, selected data obtained by the application of novel markers are presented.

Interpretation and conclusions: The present know- ledge and organization of malignant lymphomas now make the development of tailored therapies a feasible goal.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Immunophenotyping
  • Lymphoma / classification*
  • Lymphoma / immunology
  • Lymphoma / pathology
  • Lymphoma, B-Cell / classification
  • Lymphoma, B-Cell / immunology
  • Lymphoma, B-Cell / pathology
  • Lymphoma, T-Cell / classification
  • Lymphoma, T-Cell / immunology
  • Lymphoma, T-Cell / pathology
  • Practice Guidelines as Topic