Effects of theophylline on exercise indices in a patient with chronotropic incompetence

Clin Cardiol. 2000 Oct;23(10):787-9. doi: 10.1002/clc.4960231019.

Abstract

Several investigators have documented the successful use of oral sustained-release theophylline in treating symptomatic bradycardia and sick sinus syndrome. This paper reports a case of chronotropic incompetence in which specific exercise indices, including the chronotropic response index, were used to measure the therapeutic efficacy of theophylline.

Publication types

  • Case Reports
  • Clinical Trial
  • Review

MeSH terms

  • Bradycardia / diagnosis
  • Bradycardia / drug therapy*
  • Bradycardia / physiopathology
  • Delayed-Action Preparations
  • Exercise Tolerance / drug effects*
  • Heart Rate / drug effects*
  • Humans
  • Male
  • Middle Aged
  • Sick Sinus Syndrome / diagnosis
  • Sick Sinus Syndrome / drug therapy*
  • Sick Sinus Syndrome / physiopathology
  • Theophylline / therapeutic use*
  • Vasodilator Agents / therapeutic use*

Substances

  • Delayed-Action Preparations
  • Vasodilator Agents
  • Theophylline