Rapid development of Epstein-Barr virus-associated Hodgkin's disease after cessation of foscarnet therapy in an HIV-infected patient

C Schramm; J F Schlaak; P R Galle

doi:10.1258/0956462001916489

Rapid development of Epstein-Barr virus-associated Hodgkin's disease after cessation of foscarnet therapy in an HIV-infected patient

Int J STD AIDS. 2000 Sep;11(9):609-10. doi: 10.1258/0956462001916489.

Authors

C Schramm¹, J F Schlaak, P R Galle

Affiliation

¹ 1st Department of Medicine, Johannes Gutenberg University, Mainz, Germany. schramm@mail.uni.mainz.de

PMID: 10997507
DOI: 10.1258/0956462001916489

Abstract

Epidemiological features suggest a link between Hodgkin's disease (HD) and Epstein-Barr virus (EBV) infection. Indeed, EBV genome and expression of latent antigens can be found in Reed-Sternberg cells. In the majority of cases HD in HIV patients seems to be EBV-associated. We report on a 51-year-old HIV-infected patient in whom EBV-positive HD of mixed cellularity rapidly developed within one month after cessation of treatment with intravenous foscarnet.

Publication types

Case Reports

MeSH terms

Antiviral Agents / administration & dosage
Antiviral Agents / therapeutic use*
Epstein-Barr Virus Infections / etiology*
Epstein-Barr Virus Infections / prevention & control
Foscarnet / administration & dosage
Foscarnet / therapeutic use*
HIV Infections / complications*
HIV Infections / drug therapy
Hodgkin Disease / etiology*
Hodgkin Disease / prevention & control
Hodgkin Disease / virology
Humans
Male
Middle Aged

Substances

Antiviral Agents
Foscarnet