Individual experience reveals that posterior foot placement enables one to stand up easily from a chair. However, the way in which foot placement affects this motion has not been investigated in detail. This study was performed to examine the effects of foot placement in the initial stage of the dynamics of standing up from a chair. Subjects wearing light-emitting diode markers and surface electrodes stood up from a chair over force plates, and ground reaction force, joint angle, and muscle activity were measured. The motions required to stand up from chairs 30, 40, or 50 cm in height were analyzed with anterior, vertical, and posterior foot placement. With anterior foot placement, the forward-acceleration components of the ground reaction force were recorded with simultaneous and long-sustained activity of the muscles in order to shift the center of gravity of the body forward even more after lift-off. Our findings indicate that the distance between the center of gravity and the point of application of ground reaction force at lift-off are critical factors in the standing-up motion, and that chairs should be of adequate height as well as having sufficient space under the seat to permit the backward movement of the lower legs.