Melatonin but not vitamins C and E maintains glutathione homeostasis in t-butyl hydroperoxide-induced mitochondrial oxidative stress

FASEB J. 2000 Sep;14(12):1677-9. doi: 10.1096/fj.99-0865fje.
No abstract available

MeSH terms

  • Animals
  • Antioxidants / pharmacology*
  • Ascorbic Acid / pharmacology
  • Chromans / pharmacology
  • Glutathione / metabolism*
  • Glutathione Disulfide / metabolism
  • Homeostasis / drug effects*
  • Homeostasis / physiology
  • Melatonin / pharmacology
  • Mitochondria / drug effects*
  • Mitochondria / physiology
  • Oxidation-Reduction / drug effects
  • Oxidative Stress / drug effects*
  • Oxidative Stress / physiology
  • Rats
  • Vitamin E / pharmacology
  • tert-Butylhydroperoxide / pharmacology

Substances

  • Antioxidants
  • Chromans
  • Vitamin E
  • tert-Butylhydroperoxide
  • Glutathione
  • Melatonin
  • Ascorbic Acid
  • 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
  • Glutathione Disulfide