Histology of the urethral plate: implications for hypospadias repair

J Urol. 2000 Sep;164(3 Pt 2):988-9; discussion 989-90. doi: 10.1097/00005392-200009020-00017.

Abstract

Purpose: We define the histology of the urethral plate in boys with hypospadias.

Materials and methods: Subepithelial biopsies of the urethral plate were obtained in 17 boys, including 13 with distal and 4 with penoscrotal hypospadias. Ventral penile curvature was noted in 5 cases. Specimens were evaluated by 7 light microscopy after hematoxylin and eosin staining.

Results: All biopsies demonstrated well vascularized connective tissue comprised of smooth muscle and collagen. There was no evidence of fibrous bands or dysplastic tissue.

Conclusions: The urethral plate consists of epithelium overlying connective tissue. We found no histological evidence of fibrous cords historically considered responsible for chordee.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Humans
  • Hypospadias / pathology*
  • Hypospadias / surgery*
  • Male
  • Urethra / pathology*