[Investigation of ambiphilic creams. II. Structural stability]

Acta Pharm Hung. 2000 Feb;70(1):15-8.
[Article in Hungarian]

Abstract

Ambiphile creams containing white petrolatum, cetylstearyl-alcohol, Emulgator BTO and distilled water were investigated. The elements of the study of structure-stability were as follows: evaporation of water-phase, mechanical stability of structure and its heatstability. A multiplicative function was found between the loss of mass of creams and the evaporation time. The viscosity vs. temperature function is a two-steps process, it can be divided to a section before melting and an other section after it. Decreasing viscosity under shearing time can be characterized by a logarithmic equation.

Publication types

  • English Abstract

MeSH terms

  • Drug Stability
  • Excipients / chemistry*
  • Fatty Alcohols / chemistry*
  • Ointments*
  • Petrolatum / chemistry*

Substances

  • Excipients
  • Fatty Alcohols
  • Ointments
  • Petrolatum