1,3-dipolar cycloadditions as a tool for the preparation of multivalent structures

F G Calvo-Flores; J Isac-García; F Hernández-Mateo; F Pérez-Balderas; J A Calvo-Asín; E Sanchéz-Vaquero; F Santoyo-González

doi:10.1021/ol006175v

1,3-dipolar cycloadditions as a tool for the preparation of multivalent structures

Org Lett. 2000 Aug 10;2(16):2499-502. doi: 10.1021/ol006175v.

Authors

F G Calvo-Flores¹, J Isac-García, F Hernández-Mateo, F Pérez-Balderas, J A Calvo-Asín, E Sanchéz-Vaquero, F Santoyo-González

Affiliation

¹ Instituto de Biotecnología, Departamento de Química Orgánica, Facultad de Ciencias, Campus Fuentenueva s/n, Universidad de Granada, Granada E-18071,Spain.

PMID: 10956531
DOI: 10.1021/ol006175v

Abstract

The construction of multivalent structures such as sugar heterodimers, glycoclusters, calix sugars, multicalixarenes, and glycocyclodextrins is designed by using 1,3-dipolar cycloaddition as a versatile and efficient tool which allows the creation of heterocyclic bridges between the different units that are coupled.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Carbohydrate Conformation
Catalysis*
Chemistry, Organic / methods*
Dimerization
Glycoconjugates / chemical synthesis*
Glycoconjugates / chemistry*
Models, Molecular

Substances

Glycoconjugates