Chromosome 19 translocation, overexpression of Notch3, and human lung cancer

J Natl Cancer Inst. 2000 Aug 16;92(16):1355-7. doi: 10.1093/jnci/92.16.1355.
No abstract available

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Carcinoma, Non-Small-Cell Lung / genetics
  • Carcinoma, Small Cell / genetics
  • Chromosome Mapping / methods
  • Chromosomes, Human, Pair 15 / genetics*
  • Chromosomes, Human, Pair 19 / genetics*
  • Female
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Immunohistochemistry
  • Karyotyping
  • Lung Neoplasms / genetics*
  • Mesothelioma / genetics
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins / metabolism*
  • RNA, Messenger / analysis
  • Receptor, Notch3
  • Receptors, Cell Surface / genetics
  • Receptors, Cell Surface / metabolism*
  • Receptors, Notch
  • Translocation, Genetic
  • Tumor Cells, Cultured
  • Up-Regulation

Substances

  • NOTCH3 protein, human
  • Proto-Oncogene Proteins
  • RNA, Messenger
  • Receptor, Notch3
  • Receptors, Cell Surface
  • Receptors, Notch