Production and application of LPA polyclonal antibody

J H Chen; F Zou; N D Wang; S W Xie; X Zhang

doi:10.1016/s0960-894x(00)00325-5

Production and application of LPA polyclonal antibody

Bioorg Med Chem Lett. 2000 Aug 7;10(15):1691-3. doi: 10.1016/s0960-894x(00)00325-5.

Authors

J H Chen¹, F Zou, N D Wang, S W Xie, X Zhang

Affiliation

¹ Ministry of Education Key Lab of Bioorganic Chemistry & Molecular Engineering, Department of Chemistry, Peking University, Beijing, PR China. jhchem@chemms.chem.pku.edu.cn

PMID: 10937726
DOI: 10.1016/s0960-894x(00)00325-5

Abstract

By using colloidal gold as a hapten carrier, a kind of antibody against lysophosphatidic acid (LPA) was developed and used to successfully detect 500 ng/mL LPA in dot immunogold filtration assay. Such application of the LPA antibody could offer us a way to diagnose ovarian cancer at its early stage.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antibodies / chemistry
Antibodies / immunology
Antibodies / isolation & purification*
Antibody Specificity
Female
Humans
Immune Sera
Lysophospholipids / immunology*
Ovarian Neoplasms / diagnosis

Substances

Antibodies
Immune Sera
Lysophospholipids