Synthesis of (+/-)-11alpha-hydroxy-3-oxo-6alphaH,7alphaH, 10betaMe-eudesman-1,2-4,5-dien-6,12-olide

F J Moreno-Dorado; F M Guerra; F J Aladro; J M Bustamante; Z D Jorge; G M Massanet

doi:10.1021/np990537u

Synthesis of (+/-)-11alpha-hydroxy-3-oxo-6alphaH,7alphaH, 10betaMe-eudesman-1,2-4,5-dien-6,12-olide

J Nat Prod. 2000 Jul;63(7):934-8. doi: 10.1021/np990537u.

Authors

F J Moreno-Dorado¹, F M Guerra, F J Aladro, J M Bustamante, Z D Jorge, G M Massanet

Affiliation

¹ Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Apartado 40, 11510 Puerto Real, Cádiz, Spain.

PMID: 10924168
DOI: 10.1021/np990537u

Abstract

The synthesis of (+/-)-11alpha-hydroxy-3-oxo-6alphaH,7alphaH, 10betaMe-eudesman-1,2-4,5-dien-6,12-olide (1), previously isolated from Melanoselinum decipiens, is described, and its structure has been corrected.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Apiaceae / chemistry*
Lactones / chemical synthesis*
Magnetic Resonance Spectroscopy
Molecular Structure
Sesquiterpenes / chemical synthesis*
Sesquiterpenes, Eudesmane*
Spectrum Analysis

Substances

11-hydroxy-3-oxo-6H,7H-10-methyl-eudesman-1,2-4,5-dien-6,12-olide
Lactones
Sesquiterpenes
Sesquiterpenes, Eudesmane