Two novel germline mutations (Y548X and K732X) of the MLH1 gene in Czech patients with hereditary nonpolyposis colorectal cancer

Hum Mutat. 2000 Aug;16(2):181. doi: 10.1002/1098-1004(200008)16:2<181::AID-HUMU22>3.0.CO;2-R.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Signal Transducing
  • Adult
  • Base Pair Mismatch
  • Carrier Proteins
  • Colorectal Neoplasms / genetics*
  • Colorectal Neoplasms, Hereditary Nonpolyposis / genetics*
  • Female
  • Germ-Line Mutation / genetics*
  • Humans
  • Lysine / genetics*
  • Male
  • Molecular Sequence Data
  • MutL Protein Homolog 1
  • Neoplasm Proteins / genetics*
  • Nuclear Proteins
  • Polymorphism, Genetic
  • Tyrosine / genetics*

Substances

  • Adaptor Proteins, Signal Transducing
  • Carrier Proteins
  • MLH1 protein, human
  • Neoplasm Proteins
  • Nuclear Proteins
  • Tyrosine
  • MutL Protein Homolog 1
  • Lysine