Nosocomial fungaemia: a 2-year prospective study

J Hosp Infect. 2000 May;45(1):69-72. doi: 10.1053/jhin.1999.0670.

Abstract

Eighty-six consecutive patients with fungaemia were studied during a period of 2 years, 81% had two or more positive blood cultures. Gastrointestinal tract (28%) and haematological diseases (17%) were the most common underlying conditions. The majority of cases had received vancomycin and/or imipenem (87%) and a central venous catheter (78%). Candida albicans (50%) and Candida parapsilosis (17%) were the most frequent isolates. Overall mortality was 41%, and for patients with Candida tropicalis was 71%. There was not significant difference in survival with gender, age and days of treatment with antifungal drugs. Haematological diseases, neutropenia and a higher number of positive blood cultures were associated with poor outcome.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antifungal Agents / therapeutic use
  • Brazil / epidemiology
  • Candida albicans
  • Candidiasis / drug therapy
  • Candidiasis / epidemiology
  • Candidiasis / microbiology
  • Candidiasis / prevention & control
  • Child
  • Child, Preschool
  • Cross Infection / drug therapy
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Cross Infection / prevention & control
  • Female
  • Fungemia / drug therapy
  • Fungemia / epidemiology*
  • Fungemia / microbiology
  • Fungemia / prevention & control
  • Fusarium
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Pichia
  • Prospective Studies
  • Rhodotorula
  • Risk Factors
  • Survival Rate

Substances

  • Antifungal Agents