Age-related seroprevalence of Cryptosporidium in northern Israel

Isr Med Assoc J. 2000 May;2(5):343-5.

Abstract

Background: Two recent studies found that the prevalence of cryptosporidiosis among children in Israel was 3.4-7.4%.

Objectives: To assess the cumulative infection rate by testing immunoglobulin A and G seroprevalence for Cryptosporidium in children and adults in Israel.

Patients and methods: The seroprevalence of IgA and IgG anti-Cryptosporidium antibodies was determined by an enzyme-linked immunosorbent assay procedure in a group of 163 healthy children and adults.

Results: The overall seroprevalence rates for IgG, IgA, both IgA and IgG, and any immunoglobulin were 12.6%, 23%, 30% and 65.6% respectively. Half the children under the age of 12 years were already infected, with seroprevalence increasing to 95.6% in those over age 13 (P < 0.05). Seropositivity for IgG or IgA did not significantly increase with age.

Conclusions: These results indicate that a large percentage of healthy children and adults in northern Israel have been infected with Cryptosporidium, and at early ages.

MeSH terms

  • Adult
  • Animals
  • Antibodies, Protozoan / blood*
  • Child, Preschool
  • Cryptosporidiosis / epidemiology*
  • Cryptosporidium / immunology*
  • Female
  • Humans
  • Immunoglobulin A / blood
  • Immunoglobulin G / blood
  • Infant
  • Israel / epidemiology
  • Male
  • Seroepidemiologic Studies

Substances

  • Antibodies, Protozoan
  • Immunoglobulin A
  • Immunoglobulin G