Percutaneous portal vein thrombolysis and endovascular stent for management of posttransplant portal venous conduit thrombosis

Transplantation. 2000 May 27;69(10):2195-8. doi: 10.1097/00007890-200005270-00042.

Abstract

Background: Thrombosis of a portal vein conduit after liver transplant is an uncommon clinical situation. Percutaneous thrombolytic therapy for this condition has not been widely described.

Methods: We describe a case of thrombosis of a portal vein (PV) conduit subsequent to orthotopic liver transplantation that was successfully treated by percutaneous portal vein thrombolysis by using tissue plasminogen activator, angioplasty, and endovascular stent placement.

Results: A satisfactory outcome was achieved with a patent portal vein, on ultrasound, at 8-month follow-up.

Conclusion: A percutaneous transhepatic approach to treatment of thrombosis of a portal vein conduit appears to be a promising technique to use to avoid surgery, with good medium-term results.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Fibrinolytic Agents / therapeutic use
  • Heparin / therapeutic use*
  • Humans
  • Infusions, Intravenous
  • Liver Function Tests
  • Liver Transplantation* / methods
  • Liver Transplantation* / physiology
  • Middle Aged
  • Portal Vein*
  • Postoperative Complications / therapy*
  • Stents*
  • Thrombolytic Therapy*
  • Time Factors
  • Treatment Outcome
  • Venous Thrombosis / etiology
  • Venous Thrombosis / therapy*

Substances

  • Fibrinolytic Agents
  • Heparin