Siamenol, a new carbazole alkaloid from Murraya siamensis

K M Meragelman; T C McKee; M R Boyd

doi:10.1021/np990570g

Siamenol, a new carbazole alkaloid from Murraya siamensis

J Nat Prod. 2000 Mar;63(3):427-8. doi: 10.1021/np990570g.

Authors

K M Meragelman¹, T C McKee, M R Boyd

Affiliation

¹ Laboratory of Drug Discovery Research and Development, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, NCI-FCRDC, Frederick, Maryland 21702, USA.

PMID: 10757740
DOI: 10.1021/np990570g

Abstract

A new carbazole alkaloid, siamenol (1), and two known alkaloids, mahanimbine (2) and mahanimbilol (3), have been isolated from the organic extract of Murraya siamensis. The novel compound exhibited HIV-inhibitory activity.

MeSH terms

Alkaloids / chemistry
Alkaloids / isolation & purification*
Alkaloids / pharmacology
Anti-HIV Agents / chemistry
Anti-HIV Agents / isolation & purification*
Anti-HIV Agents / pharmacology
Carbazoles / chemistry
Carbazoles / isolation & purification*
Carbazoles / pharmacology
Molecular Structure
Plants, Medicinal / chemistry*
Spectrum Analysis

Substances

Alkaloids
Anti-HIV Agents
Carbazoles
siamenol