[Antibiotic prophylaxis in cesarean section]

Rev Med Chir Soc Med Nat Iasi. 1997 Jan-Jun;101(1-2):156-9.
[Article in Romanian]

Abstract

The purpose of this study was to investigate the efficacy of prophylactic antibiotics in preventing pelvic infection after cesarean section. A randomized, prospective study was carried out between January 1, 1994 and May 15, 1995. There had been involved 657 women without significant obstetrical differences. 305 of them were excluded from analysis, for have received antibiotherapy after operation. 182 women received prophylactic antibiotics (group B) consisting of certain combinations, given in one dose. 170 women constituted the witnesses' group (A). The rate of postoperative infection in the group who had received antibiotic prophylaxis (group B) was lower (15.93%--29 women) than in the group A (32.35%--55 women who had postoperative infection). Therefore, antibiotic prophylaxis reduced the frequency of infections after cesarean section for 2.03 times.

In conclusion: Prophylactic antibiotics are effective in preventing pelvic infections after cesarean section.

Publication types

  • Clinical Trial
  • Comparative Study
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anti-Bacterial Agents*
  • Antibiotic Prophylaxis / methods*
  • Cesarean Section*
  • Drug Therapy, Combination / therapeutic use*
  • Female
  • Humans
  • Pregnancy
  • Prospective Studies
  • Surgical Wound Infection / prevention & control

Substances

  • Anti-Bacterial Agents