Seroepidemiology of Hantavirus in the Philippines

Int J Infect Dis. 2000;4(2):104-7. doi: 10.1016/s1201-9712(00)90103-6.

Abstract

Objective: This study was undertaken to determine the seroepidemiology of Hantavirus infection in the Philippines.

Methods: This is a cross-sectional study done in asymptomatic volunteers from various communities in the Philippines selected by a stratified multistage sampling design. Antibody to Hantavirus was detected by particle agglutination (PA) test using Hantadia high-density particle agglutination (HDPA) reagent kit.

Results: The prevalence of positive Hantavirus antibody among 461 subjects was the same in both males (6.1%) and females (6.1%) in rural (7.6%), urban (5.6%), and urban poor (5.1%) populations.

Conclusions: The prevalence of Hantavirus infection in the Filipino population is comparable to that seen in other developing countries. The HDPA can be conveniently used as a rapid tool to detect the Hantavirus antibody for seroepidemiologic and diagnostic purposes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Agglutination Tests / methods
  • Antibodies, Viral / blood*
  • Cross-Sectional Studies
  • Female
  • Hantavirus Infections / epidemiology*
  • Hantavirus Infections / virology
  • Humans
  • Male
  • Middle Aged
  • Orthohantavirus / immunology*
  • Philippines / epidemiology
  • Prevalence
  • Rural Population
  • Seroepidemiologic Studies
  • Urban Population

Substances

  • Antibodies, Viral