Abstract
Plants synthesize numerous secondary metabolites that are used as developmental signals or as defense against pathogens. Tryptophan (Trp)-derived secondary metabolites include camalexin, indole glucosinolates, and indole-3-acetic acid (IAA); however, the steps in their synthesis from Trp or its precursors remain unclear. We have identified two Arabidopsis cytochrome P450s (CYP79B2 and CYP79B3) that can convert Trp to indole-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amino Acid Sequence
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Arabidopsis / genetics
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Arabidopsis Proteins / genetics
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Arabidopsis Proteins / isolation & purification
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Arabidopsis Proteins / metabolism*
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Catalysis
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Cytochrome P-450 Enzyme System / genetics
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Cytochrome P-450 Enzyme System / isolation & purification
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Cytochrome P-450 Enzyme System / metabolism*
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Genes, Plant
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Indoleacetic Acids / metabolism*
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Molecular Sequence Data
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Oximes / metabolism
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Plants, Genetically Modified
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Pseudomonas / physiology
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Tryptophan / metabolism*
Substances
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Arabidopsis Proteins
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Indoleacetic Acids
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Oximes
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indoleacetic acid
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Tryptophan
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Cytochrome P-450 Enzyme System
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cytochrome P-450 79B3, Arabidopsis
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acetaldehyde oxime