Abstract
Escherichia coli biofilms on two polyethylene disks were implanted subcutaneously into rabbits receiving systemic gentamicin. Ultrasound was applied for 24 h to one disk. Both disks were removed, and viable bacteria were counted. Pulsed ultrasound significantly reduced bacterial viability below that of nontreated biofilms without damage to the skin.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Anti-Bacterial Agents / pharmacology*
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Biofilms / drug effects*
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Biofilms / growth & development
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Escherichia coli / drug effects*
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Escherichia coli / growth & development
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Escherichia coli Infections / microbiology
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Gentamicins / pharmacology*
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Prosthesis-Related Infections / microbiology
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Rabbits
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Ultrasonics*
Substances
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Anti-Bacterial Agents
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Gentamicins