The in vitro effect of dandelions antioxidants on microsomal lipid peroxidation

K Hagymási; A Blázovics; J Fehér; A Lugasi; S T Kristó; A Kéry

doi:10.1002/(sici)1099-1573(200002)14:1<43::aid-ptr522>3.3.co;2-h

The in vitro effect of dandelions antioxidants on microsomal lipid peroxidation

Phytother Res. 2000 Feb;14(1):43-4. doi: 10.1002/(sici)1099-1573(200002)14:1<43::aid-ptr522>3.3.co;2-h.

Authors

K Hagymási¹, A Blázovics, J Fehér, A Lugasi, S T Kristó, A Kéry

Affiliation

¹ II. Department of Medicine, Semmelweis University Medical School, Budapest, Hungary.

PMID: 10641047
DOI: 10.1002/(sici)1099-1573(200002)14:1<43::aid-ptr522>3.3.co;2-h

Abstract

Dandelions have long been used in herbal medicine for their choleretic, diuretic, antiinflammatory, appetite-stimulating and laxative properties. An antioxidant property can be supposed as a basis of their-therapeutic effects. To understand the mechanism of the drug's action, the effects of natural extracts on a microsomal fraction of rat liver were examined. The extracts diminished the enzymatically induced-lipid peroxidation and reduced the cytochrome c with and without NADPH in a concentration dependent manner.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antioxidants / pharmacology*
Lipid Peroxidation / drug effects*
Microsomes, Liver / drug effects*
Microsomes, Liver / metabolism
Plant Extracts / pharmacology*
Plants, Medicinal / chemistry*
Rats

Substances

Antioxidants
Plant Extracts