Postoperative analgesia after arthroscopic knee surgery: a randomized, prospective, double-blind study of intravenous regional analgesia versus intra-articular analgesia

Arthroscopy. 2000 Jan-Feb;16(1):64-6. doi: 10.1016/s0749-8063(00)90129-4.

Abstract

The aim of this study was to determine the quality of postoperative analgesia in patients undergoing arthroscopic knee surgery using preoperative intravenous regional analgesia. After initial consultation with a statistician, we allocated 36 patients randomly and double-blind to 1 of 3 groups. Group A received intravenous regional analgesia preoperatively, group B received standard postperative intra-articular analgesia, and group C received saline and acted as the placebo. Our results showed no statistically significant difference in pain levels between the groups. However, there was a significantly larger amount of morphine administered by patient-controlled pumps in the placebo group when compared with the 2 treatment groups. There was no such difference between the 2 treatment groups. We concluded that preoperative regional analgesia in this setting is as good as but no better than intra-articular analgesia and that neither technique has any advantages over diclofenac plus patient-controlled analgesia.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adjuvants, Anesthesia / administration & dosage
  • Analgesia, Patient-Controlled / methods*
  • Analgesics, Opioid / administration & dosage*
  • Anesthetics, Local / administration & dosage*
  • Anterior Cruciate Ligament / surgery*
  • Arthroscopy*
  • Bupivacaine / administration & dosage
  • Double-Blind Method
  • Droperidol / administration & dosage
  • Drug Therapy, Combination
  • Humans
  • Injections, Intra-Articular
  • Injections, Intravenous
  • Morphine / administration & dosage
  • Pain Measurement
  • Pain, Postoperative / drug therapy*
  • Prospective Studies
  • Treatment Outcome

Substances

  • Adjuvants, Anesthesia
  • Analgesics, Opioid
  • Anesthetics, Local
  • Morphine
  • Droperidol
  • Bupivacaine