With increasing interest in detrusor disorders and possible detrusor myopathies, a method for recording the detrusor electromyogram (detrusor-EMG) would probably greatly assist the diagnosis of various bladder dysfunctions. Therefore, we investigated the electromyographic activity of the detrusor during sacral root stimulation and during spontaneous bladder contractions in six anesthetized dogs. In all experiments, a high correlation of detrusor-EMG recordings with bladder contraction was observed. Analysis in the time domain and power spectrum analysis revealed the most clear correlation of detrusor-EMG with intravesical pressure rise in a frequency band above 3 Hz. The spike duration was 100 to 250 ms with an amplitude of 100 to 500 microV. Low-frequency activity below 1 Hz was mainly presumed to be artifacts due to fluid movement under the electrode. Our trials indicate that smooth muscle EMG recordings from the detrusor smooth musculature are possible. The exact physiological relevance of the signal in the sub-Hertz domain (<1 Hz) is still uncertain. The presented animal model allows the pathophysiologic investigation of various pathologies of bladder dysfunction and detrusor myopathies. Neurourol. Urodynam. 18:687-695, 1999.
Copyright 1999 Wiley-Liss, Inc.