Occurrence of an unusual lactose sulfate in dog milk

Carbohydr Res. 1999 May 31;318(1-4):123-8. doi: 10.1016/s0008-6215(99)00102-0.

Abstract

The milk of a beagle dog (Canis familiaris) was extracted and fractionated to yield, inter alia, beta-D-Galp3S-(1-->4)-D-Glc (lactose 3'-sulfate), which does not appear to have previously been isolated from milk or other natural sources. The structure was established by 2D NMR spectroscopy and mass spectrometry. By contrast with the milk of some closely related Carnivora, the major constituent of the dog milk was lactose, with minor amounts of 2'-fucosyllactose and sialyl oligosaccharides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromatography, Thin Layer
  • Dogs
  • Female
  • Lactose / analogs & derivatives*
  • Lactose / analysis
  • Lactose / chemistry
  • Lactose / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Milk / chemistry*
  • Oligosaccharides / chemistry
  • Oligosaccharides / isolation & purification*
  • Sulfuric Acid Esters / analysis*
  • Sulfuric Acid Esters / chemistry
  • Sulfuric Acid Esters / isolation & purification

Substances

  • Oligosaccharides
  • Sulfuric Acid Esters
  • lactose 3'-sulfate
  • Lactose