100 cases of patients under cancer chemotherapy were investigated by using Self-Rating Anxiety Scale (SAS) and questionnaire on coping patterns. The results showed that scores of SAS were significantly higher than that of the normal population. The state of the anxiety reached 45% among the patients. The patients' coping patterns tended to be passive. Linear analysis revealed a negative correlation between the coping patterns and the scores of SAS. It is recommended that cognitive behavioral therapy can be used to relieve the anxiety of patients under cancer chemotherapy.