Objective: To observe abnormal cell multiplication in rabbits ciliary sulcus with posterior chamber intraocular lens (PC-IOL) implantation and ciliary sulcus fixation technique.
Methods: 96 New Zealand rabbits were implanted with PC-IOL, and they were divided into two groups: one with ciliary sulcus suture fixation and the other without the suture fixation. The eyeballs were extracted at the following postoperative times: 1/2, 1, 2, 3 months. The reactions of the proliferating cell nuclear antigen (PCNA) in ciliary sulcus of the rabbits were studied with immunohistochemistry technique in the above two groups and the normal control group.
Results: There was no abnormal proliferating cell reaction in ciliary sulcus of the rabbits with the two methods of PC-IOL implantation techniques.
Conclusions: IOL ciliary sulcus suture fixation is a convenient method for PC-IOL implantation under the circumstance when rupture of the posterior capsule occurs intraoperatively or in the second stage implantation.