Aim: To investigate the relationship between Helicobacter pylori infection and ulcer in population of Khakasiia.
Materials and methods: An epidemiological study of dyspepsia and ulcer prevalence in Khakasiia population covered 1052 patients (564 residents and 488 immigrants). 339 patients were examined endoscopically. Helicobacter pylori (HP) was detected in gastric mucosa using light microscopy after Giemsa staining in 214 patients (104 immigrants and 110 residents).
Results: Prevalence of ulcer and HP were 6.1, 1.5% and 69.2 and 88.9% in immigrants and residents, respectively. HP index, degree of dissemination and adhesion in gastric mucosa of immigrants with duodenal ulcer were higher than in controls. The same but less manifest tendency was in the residents.
Conclusion: The population of the Siberian South has ethnic features of ulcer prevalence and pathogenesis. It is thought more valid to study mechanisms of ulcerogenesis through quantitative rather than qualitative characteristics of HP infection.