Abstract
The presence and distribution of the glutamate transporters, EAAC1, GLAST and GLT-1, were examined in the adult bovine corpus callosum by means of Western blotting and immunohistochemistry. We found GLAST to be expressed in oligodendrocytes and in some astrocytes. GLT-1 was located throughout the processes of fibrous astrocytes. In addition, EAAC1 was present in a small population of cells that are probably adult oligodendrocyte progenitor cells.
Copyright 1999 Elsevier Science B.V.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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2',3'-Cyclic-Nucleotide Phosphodiesterases / analysis
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ATP-Binding Cassette Transporters / analysis
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ATP-Binding Cassette Transporters / genetics
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ATP-Binding Cassette Transporters / metabolism
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Age Factors
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Amino Acid Transport System X-AG
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Animals
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Astrocytes / chemistry
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Astrocytes / metabolism
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Blotting, Western
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Carrier Proteins / analysis
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Carrier Proteins / genetics*
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Carrier Proteins / metabolism
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Cattle
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Cell Size / physiology
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Corpus Callosum / chemistry*
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Corpus Callosum / cytology
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Corpus Callosum / metabolism
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Fluorescent Antibody Technique
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Gene Expression / physiology
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Glial Fibrillary Acidic Protein / analysis
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Glutamate Plasma Membrane Transport Proteins
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Glutamic Acid / metabolism*
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Homeostasis / genetics
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Intermediate Filament Proteins / analysis
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Nerve Tissue Proteins*
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Nestin
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Neurons / chemistry
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Neurons / cytology
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Oligodendroglia / chemistry
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Oligodendroglia / enzymology
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Stem Cells / chemistry
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Stem Cells / enzymology
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Symporters*
Substances
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ATP-Binding Cassette Transporters
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Amino Acid Transport System X-AG
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Carrier Proteins
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Glial Fibrillary Acidic Protein
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Glutamate Plasma Membrane Transport Proteins
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Intermediate Filament Proteins
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Nerve Tissue Proteins
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Nestin
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Symporters
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Glutamic Acid
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2',3'-Cyclic-Nucleotide Phosphodiesterases