[Spinocerebellar ataxia and polyneuropathy secondary to vitamin E deficiency]

Presse Med. 1999 Mar 13;28(10):524-6.
[Article in French]

Abstract

Background: Cerebellar ataxia or peripheral neuropathy can be signs of vitamin E deficiency. We report two cases.

Case reports: Two patients developed vitamin E deficiency subsequent to intestinal malabsorption. The first patient had a duodenogastric communication and dilatation of the first jejunal loop. The second patient had deficient pancreas secretion and dilatation of the biliary tree.

Discussion: Vitamin E deficiency is generally secondary to acquired or hereditary malabsorption syndrome. It can also occur in the absence of malabsorption by hereditary deficiency in alpha-tocopherol transporter. Vitamin E supplements are required for malabsorption. The etiology work-up of neuropathy or cerebellar ataxia should include vitamin E assay.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adolescent
  • Electromyography
  • Female
  • Humans
  • Malabsorption Syndromes / complications
  • Middle Aged
  • Peripheral Nervous System Diseases / diagnosis
  • Peripheral Nervous System Diseases / etiology*
  • Sensation Disorders / diagnosis
  • Sensation Disorders / etiology
  • Spinocerebellar Degenerations / diagnosis
  • Spinocerebellar Degenerations / etiology*
  • Vitamin E / therapeutic use
  • Vitamin E Deficiency / complications*
  • Vitamin E Deficiency / drug therapy
  • Vitamin E Deficiency / etiology

Substances

  • Vitamin E