Adhesive proteins of the malaria parasite

Curr Opin Microbiol. 1998 Aug;1(4):472-81. doi: 10.1016/s1369-5274(98)80068-4.

Abstract

Malaria infection of the host cells requires host-parasite recognition events mediated by adhesion and signaling molecules. Recent development of systems for stable transformation and targeted integration of exogenous DNA in malaria parasites provides a powerful tool to study the structure and function of Plasmodium attachment motifs, and their role in infection and disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Cell Adhesion
  • Cell Adhesion Molecules / genetics
  • Cell Adhesion Molecules / metabolism*
  • Erythrocytes / parasitology
  • Liver / parasitology
  • Malaria / parasitology*
  • Molecular Sequence Data
  • Plasmodium / genetics
  • Plasmodium / pathogenicity*
  • Protozoan Proteins / genetics
  • Protozoan Proteins / metabolism*

Substances

  • Cell Adhesion Molecules
  • Protozoan Proteins