Spontaneous splenic rupture as the initial symptom of splenic angiosarcoma: case report and literature review

Peiwu Jiang; Xiaowen Li; Jie Chen; Du Li; Yehong Han

doi:10.3389/fonc.2024.1366554

Spontaneous splenic rupture as the initial symptom of splenic angiosarcoma: case report and literature review

Front Oncol. 2024 May 2:14:1366554. doi: 10.3389/fonc.2024.1366554. eCollection 2024.

Authors

Peiwu Jiang¹, Xiaowen Li², Jie Chen², Du Li³, Yehong Han²

Affiliations

¹ Department of Vascular Surgery, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.
² Department of General Surgery, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.
³ Department of Pathology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.

Abstract

Spontaneous splenic rupture is an extremely rare occurrence, often attributed to tumorous pathologies. Among these, primary splenic angiosarcoma stands as a malignancy arising from the endothelial cells within the spleen. While sporadic cases have been reported globally, there remains a lack of comprehensive consensus on standardized approaches for diagnosis and treatment. We report a case of an 83-year-old male who underwent emergency enhanced CT due to sudden shock, revealing significant intra-abdominal fluid accumulation. Emergency surgery revealed splenic rupture necessitating splenectomy. Histopathological examination confirmed the diagnosis of splenic angiosarcoma. Despite successful surgery, the patient succumbed to severe complications two weeks postoperatively.

Keywords: angiosarcoma; case reprot; immunohistochemistry; spleen; splenectomy; splenic rupture.

Publication types

Case Reports

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by Zhejiang Traditional Medicine and Technology Program, China(Grant No.2024ZL625).